Download the official Zebra ZD421c driver to enable reliable thermal transfer printing with easy-to-load ribbon cartridges. The ZD421c is designed for users who value simple maintenance and consistent label quality across healthcare, retail, and logistics environments.
Product Name: Zebra ZD421c
Model: ZD421c Cartridge-based Thermal Transfer Printer
Printer Type: Label Printer (Thermal Transfer – Cartridge)
Connectivity: USB / USB Host / Optional Ethernet, Wi-Fi, Serial
Click below to download the certified driver for Windows systems.
Supported Operating Systems
- Windows 7 (64-bit)
- Windows 8 (64-bit)
- Windows 10 (64-bit)
- Windows 11 (64-bit)
To view manuals, firmware updates, or connection options, visit Zebra’s official ZD421c page:
👉 Visit Zebra ZD421c Official Support
Troubleshooting and Additional Help
If the printer fails to detect the ribbon cartridge or stops during printing, open the cover, remove and reinsert the cartridge properly, and check driver settings within Windows.
👉 Go to Printer Troubleshooting Guide
ZebraDesigner 3.3 Essentials & Professional
ZebraDesigner 3.3 allows users to quickly build and print labels using drag-and-drop tools. ZD421c is fully supported, and you can use the free Essentials version or trial the Professional edition.
Note: To activate Professional features, a valid Zebra Customer ID and License Key is required. Keys beginning with 3467 are incompatible due to Thales licensing restrictions.